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Ketoconazole Coadministration of bosentan a hundred twenty five mg two times daily and ketoconazole, a strong CYP3A inhibitor, amplified the plasma concentrations of bosentan by close to a hundred% in usual volunteers. No dose adjustment of bosentan is essential, but enhanced effects of bosentan really should be regarded. Lastly, endothelial https://bosentan56319.ka-blogs.com/79194100/the-single-best-strategy-to-use-for-bosentan

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