Here, we show that conolidine, a natural analgesic alkaloid Employed in standard Chinese medicine, targets ACKR3, therefore offering added evidence of the correlation involving ACKR3 and discomfort modulation and opening different therapeutic avenues to the treatment method of Persistent soreness. A: Conolidine is mainly known for potentially easing discomfort, https://georgesw592aws1.wikidirective.com/user