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Opioid action is due to both equally small affinity binding of your dad or mum compound and better affinity binding in the O-demethylated metabolite M1 to µ-opioid receptors. In animal products, M1 is around 6 situations extra potent than tramadol in manufacturing analgesia and 200 situations far more powerful in https://raymondg025liw9.idblogmaker.com/profile

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