There is a launch of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors within the dorsal horn to lessen afferent soreness transmission and develop analgesia. As a result, medications like clonidine that concentrate on alpha-two receptors can affect the transmission of soreness. Jun 10, 2024 · https://georgesq823xqj6.p2blogs.com/profile