Here, we show that conolidine, a pure analgesic alkaloid Employed in classic Chinese drugs, targets ACKR3, thereby delivering more evidence of the correlation between ACKR3 and soreness modulation and opening alternative therapeutic avenues to the cure of Serious pain. We demonstrated that, in contrast to classical opioid receptors, ACKR3 https://ingmarx840phx6.sunderwiki.com/user